
I recently worked with a woman named Sarah, a 38-year-old mother of two from Westminster, Colorado. She had tried everything to lose weight—strict diets, intense workouts, and expensive supplements—but nothing seemed to work. No matter how disciplined she was, the scale barely budged. After years of frustration, she was finally diagnosed with hypothyroidism. Like many others, Sarah had no idea her underactive thyroid was slowing her metabolism and making weight loss nearly impossible.
If you’ve been struggling with stubborn weight gain despite your best efforts, you’re not alone. Studies show that up to 60% of people with thyroid disorders are unaware they have one, which means millions of people are fighting an uphill battle with their weight without knowing the root cause. Hypothyroidism affects metabolism, energy levels, and the way your body processes calories, making traditional weight loss methods less effective.
The good news? Science-backed treatments like Semaglutide (injections, pills, and sublingual options) and other medical weight loss solutions can help those with hypothyroidism lose weight safely and effectively. In this guide, we’ll explore the best weight loss medication for hypothyroidism, how it works, and where to get expert support in Westminster, Colorado.
Understanding Hypothyroidism and Weight Gain
What is Hypothyroidism?
Hypothyroidism is a condition where the thyroid gland does not produce enough hormones to regulate metabolism. This leads to fatigue, slow digestion, water retention, and weight gain. Since the thyroid controls how your body burns calories, an underactive thyroid can make it feel like your body is working against you.
Common symptoms of hypothyroidism include:
- Unexplained weight gain
- Constant fatigue, even after a full night’s sleep
- Cold sensitivity
- Dry skin and hair loss
- Brain fog and trouble concentrating
- Slow heart rate and depression
If you’re experiencing these symptoms, it’s crucial to get tested for thyroid issues. Blood tests measuring TSH (thyroid-stimulating hormone), T3, and T4 levels can help diagnose hypothyroidism. Once diagnosed, finding the right weight loss approach can make a world of difference.
The Best Weight Loss Medication for Hypothyroidism
For those with hypothyroidism, traditional weight loss strategies alone may not be enough. Medications that support metabolism, appetite control, and insulin resistance can make losing weight more achievable. Here are some of the best options:
1. Semaglutide (Ozempic, Wegovy, and Rybelsus)
One of the most effective weight loss medications available today is Semaglutide. Originally developed for diabetes, this GLP-1 receptor agonist is now widely used for weight loss. It helps people with hypothyroidism by:
- Slowing digestion, making you feel full longer
- Reducing cravings, leading to natural calorie reduction
- Regulating blood sugar levels, which can be out of balance in hypothyroidism
- Improving insulin sensitivity, which can be impaired by thyroid dysfunction
Semaglutide is available in different forms:
- Injectable (Wegovy, Ozempic) – Weekly shots for long-term weight loss support.
- Pill form (Rybelsus) – A daily oral option for those who prefer to avoid injections.
- Sublingual Semaglutide – Dissolves under the tongue, offering a needle-free alternative.
Many patients with hypothyroidism find Semaglutide particularly effective because it helps counteract the slow metabolism and insulin resistance that often come with thyroid disorders.
2. Liothyronine (T3 Therapy)
For some, standard thyroid medications like levothyroxine (T4) aren’t enough. Adding Liothyronine (T3) can help boost metabolism, increase energy levels, and enhance weight loss results. A doctor can determine if this combination is right for you.
3. Low-Dose Naltrexone (LDN)
LDN is a lesser-known treatment that helps with inflammation, autoimmunity, and weight loss. Some people with hypothyroidism (especially Hashimoto’s) respond well to this medication, experiencing reduced hunger, improved energy levels, and a reduction in inflammatory symptoms.
4. Phentermine-Topiramate (Qsymia)
This FDA-approved medication works by suppressing appetite and boosting metabolism. While not specific to hypothyroidism, it can help those struggling with severe weight gain when combined with other treatments.
Lifestyle Changes to Support Weight Loss with Hypothyroidism

While medication provides a huge advantage, pairing it with the right lifestyle habits can maximize results. Here’s what works best:
1. Eat a Thyroid-Supportive Diet
- Prioritize protein and fiber to keep you full and support muscle maintenance.
- Avoid processed carbs and sugars that can spike insulin and slow metabolism.
- Incorporate iodine-rich foods like seaweed, eggs, and dairy to support thyroid function.
- Consume selenium-rich foods (Brazil nuts, tuna, and eggs) to aid thyroid hormone production.
2. Strength Training and Low-Impact Cardio
- Weight training helps counteract the muscle loss that slows metabolism.
- Walking, swimming, or yoga are excellent for low-energy days when intense workouts feel impossible.
3. Manage Stress and Sleep

- Poor sleep and high stress can disrupt weight loss by raising cortisol levels and increasing fat storage.
- Prioritize 7-9 hours of quality sleep and practice stress-reducing techniques like meditation or deep breathing.
Additional FAQs About Weight Loss and Hypothyroidism
1. Can hypothyroidism cause weight gain even if I eat healthy?
Yes, even with a healthy diet, hypothyroidism can slow metabolism, making it harder to lose weight. Medications and lifestyle adjustments can help counteract this effect.
2. Does drinking more water help with hypothyroid-related weight gain?
Staying hydrated can help with metabolism, digestion, and reducing water retention, but it alone is not a solution for weight loss with hypothyroidism.
3. Are there any natural supplements that support weight loss with hypothyroidism?
Some supplements, like selenium, zinc, and ashwagandha, may support thyroid function, but they should not replace medical treatments or prescribed medications.
4. How do I know if my weight loss plateau is due to my thyroid?
If you’re following a weight loss plan but not seeing progress, checking your thyroid levels with a doctor can help determine if adjustments to medication or treatment are needed.
How Go Figure Health Can Help You
At Go Figure Health, we specialize in medical weight loss solutions designed for people struggling with thyroid-related weight gain. If you’re in Westminster, Colorado, and feel stuck, we’re here to help with proven treatments like Semaglutide, customized nutrition plans, and expert medical guidance.
Why Choose Us?
✅ Personalized weight loss plans tailored to hypothyroidism
✅ Access to Semaglutide injections, pills, and sublingual options
✅ Medical professionals who understand thyroid disorders
✅ Supportive, science-backed weight loss strategies
📍 Address: 8471 Turnpike Drive, Suite 200, Westminster, Colorado, 80031
📞 Call us today: 720-513-0001
💻 Book your consultation now!
Don’t let hypothyroidism control your weight—take charge today with Go Figure Health!